According to Osho, self-knowledge is possible only when you drop all preconceptions. Any prior belief — even that an inner self exists — becomes a hindrance, strengthens the ego, and turns inquiry into proof-seeking. Keep the mind conceptless, undecided, and open; let experience come first and conclusions follow. True, scientific investigation of the inner arises from childlike not-knowing, where curiosity is free of beliefs.
Yes—if you let go of all beliefs and look inside with a fresh, childlike mind, deciding only after you actually experience.