According to Osho, this sutra calls desire (kāma) the greatest disease—not mere sex, but the restless urge for “more,” whether of wealth, power, prestige, even heaven. Repressing it breeds hypocrisy and redirects the same energy into greed or violence. Only understanding and meditative awareness transform desire; otherwise moha (delusion) becomes the enemy, krodha (anger) the consuming fire, and only jñāna yields real happiness.
Desire is the itch for more; pushing it down backfires, but seeing it clearly with awareness dissolves it and brings real peace.